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» Scoring functions and enrichment: a case study on Hsp90
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BMCBI
2007
65views more  BMCBI 2007»
13 years 4 months ago
Scoring functions and enrichment: a case study on Hsp90
Chrysi Konstantinou-Kirtay, John B. O. Mitchell, J...
BMCBI
2010
122views more  BMCBI 2010»
12 years 11 months ago
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Troy Hawkins, Meghana Chitale, Daisuke Kihara
WOB
2007
13 years 6 months ago
Gene Set Enrichment Analysis Using Non-parametric Scores
Abstract. Gene Set Enrichment Analysis (GSEA) is a well-known technique used for studying groups of functionally related genes and their correlation with phenotype. This method cre...
Ariel E. Bayá, Mónica G. Larese, Pab...
WABI
2004
Springer
106views Bioinformatics» more  WABI 2004»
13 years 10 months ago
Suboptimal Local Alignments Across Multiple Scoring Schemes
Abstract. Sequence alignment algorithms have a long standing tradition in bioinformatics. In this paper, we formulate an extension to existing local alignment algorithms: local ali...
Morris Michael, Christoph Dieterich, Jens Stoye
BMCBI
2010
101views more  BMCBI 2010»
13 years 4 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...