Sciweavers

162 search results - page 3 / 33
» Scoring functions for transcription factor binding site pred...
Sort
View
RECOMB
2003
Springer
14 years 6 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
BMCBI
2010
167views more  BMCBI 2010»
13 years 6 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
ICMLA
2010
13 years 3 months ago
Using Randomised Vectors in Transcription Factor Binding Site Predictions
Finding the location of binding sites in DNA is a difficult problem. Although the location of some binding sites have been experimentally identified, other parts of the genome may ...
Faisal Rezwan, Yi Sun, Neil Davey, Rod Adams, Alis...
RECOMB
2005
Springer
14 years 6 months ago
Predicting Transcription Factor Binding Sites Using Structural Knowledge
Abstract. Current approaches for identification and detection of transcription factor binding sites rely on an extensive set of known target genes. Here we describe a novel structu...
Tommy Kaplan, Nir Friedman, Hanah Margalit
BMCBI
2008
90views more  BMCBI 2008»
13 years 6 months ago
Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
Jakub Orzechowski Westholm, Feifei Xu, Hans Ronne,...