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BMCBI
2007
112views more  BMCBI 2007»
13 years 5 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2008
108views more  BMCBI 2008»
13 years 5 months ago
Signature Evaluation Tool (SET): a Java-based tool to evaluate and visualize the sample discrimination abilities of gene express
Background: The identification of specific gene expression signature for distinguishing sample groups is a dominant field in cancer research. Although a number of tools have been ...
Chih-Hung Jen, Tsun-Po Yang, Chien-Yi Tung, Shu-Ha...
BMCBI
2006
200views more  BMCBI 2006»
13 years 5 months ago
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data
Background: Numerous feature selection methods have been applied to the identification of differentially expressed genes in microarray data. These include simple fold change, clas...
Ian B. Jeffery, Desmond G. Higgins, Aedín C...
BMCBI
2006
146views more  BMCBI 2006»
13 years 5 months ago
Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Satoshi Niijima, Satoru Kuhara