15 search results - page 1 / 3 » Selection of antisense oligonucleotides based on multiple pr... |
BMCBI
2006
13 years 4 months ago
2006
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
WABI
2009
Springer
13 years 11 months ago
2009
Springer
Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. ...
BMCBI
2004
13 years 4 months ago
2004
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
BMCBI
2006
13 years 4 months ago
2006
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
BMCBI
2010
13 years 4 months ago
2010
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...