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» Selection of antisense oligonucleotides based on multiple pr...
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BMCBI
2010
120views more  BMCBI 2010»
13 years 5 months ago
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
GCB
2005
Springer
98views Biometrics» more  GCB 2005»
13 years 11 months ago
Composite Module Analyst: A Fitness-Based Tool for Prediction of Transcription Regulation
: Functionally related genes involved in the same molecular-genetic, biochemical, or physiological process are often regulated coordinately Such regulation is provided by precisely...
Alexander E. Kel, Tatiana Konovalova, Tagir Valeev...
BMCBI
2008
133views more  BMCBI 2008»
13 years 5 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...
RECOMB
2005
Springer
14 years 6 months ago
Recognition of Binding Patterns Common to a Set of Protein Structures
We present a novel computational method, MultiBind, for recognition of binding patterns common to a set of protein structures. It is the first method which performs a multiple alig...
Maxim Shatsky, Alexandra Shulman-Peleg, Ruth Nussi...
BMCBI
2007
164views more  BMCBI 2007»
13 years 5 months ago
SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
Fathi Elloumi, Martha Nason