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BMCBI
2007
128views more  BMCBI 2007»
13 years 5 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BMCBI
2008
130views more  BMCBI 2008»
13 years 5 months ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...
NIPS
2004
13 years 6 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
NAR
2007
91views more  NAR 2007»
13 years 4 months ago
RNABindR: a server for analyzing and predicting RNA-binding sites in proteins
Understanding interactions between proteins and RNA is key to deciphering the mechanisms of many important biological processes. Here we describe RNABindR, a web-based server that...
Michael Terribilini, Jeffry D. Sander, Jae-Hyung L...
BMCBI
2010
125views more  BMCBI 2010»
13 years 5 months ago
A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins
Background: Several bioinformatic approaches have previously been used to find novel sites of ADAR mediated A-to-I RNA editing in human. These studies have discovered thousands of...
Mats Ensterö, Örjan Åkerborg, Dani...