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» Sequence Alignment Algorithms for Run-Length-Encoded Strings
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TCBB
2010
114views more  TCBB 2010»
13 years 3 months ago
Cache-Oblivious Dynamic Programming for Bioinformatics
— We present efficient cache-oblivious algorithms for some well-studied string problems in bioinformatics including the longest common subsequence, global pairwise sequence alig...
Rezaul Alam Chowdhury, Hai-son Le, Vijaya Ramachan...
STOC
2000
ACM
156views Algorithms» more  STOC 2000»
13 years 9 months ago
Near optimal multiple alignment within a band in polynomial time
Multiple sequence alignment is a fundamental problem in computational biology. Because of its notorious difficulties, aligning sequences within a constant band (c-diagonal) is a ...
Ming Li, Bin Ma, Lusheng Wang
WABI
2004
Springer
106views Bioinformatics» more  WABI 2004»
13 years 10 months ago
Suboptimal Local Alignments Across Multiple Scoring Schemes
Abstract. Sequence alignment algorithms have a long standing tradition in bioinformatics. In this paper, we formulate an extension to existing local alignment algorithms: local ali...
Morris Michael, Christoph Dieterich, Jens Stoye
CPM
2006
Springer
112views Combinatorics» more  CPM 2006»
13 years 9 months ago
Local Alignment of RNA Sequences with Arbitrary Scoring Schemes
Abstract. Local similarity is an important tool in comparative analysis of biological sequences, and is therefore well studied. In particular, the Smith-Waterman technique and its ...
Rolf Backofen, Danny Hermelin, Gad M. Landau, Oren...
BMCBI
2008
103views more  BMCBI 2008»
13 years 5 months ago
TOPS++FATCAT: Fast flexible structural alignment using constraints derived from TOPS+ Strings Model
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
Mallika Veeramalai, Yuzhen Ye, Adam Godzik