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BMCBI
2008
120views more  BMCBI 2008»
13 years 5 months ago
Shape-IT: new rapid and accurate algorithm for haplotype inference
Background: We have developed a new computational algorithm, Shape-IT, to infer haplotypes under the genetic model of coalescence with recombination developed by Stephens et al in...
Olivier Delaneau, Cédric Coulonges, Jean-Fr...
BMCBI
2007
131views more  BMCBI 2007»
13 years 4 months ago
ISHAPE: new rapid and accurate software for haplotyping
Background: We have developed a new haplotyping program based on the combination of an iterative multiallelic EM algorithm (IEM), bootstrap resampling and a pseudo Gibbs sampler. ...
Olivier Delaneau, Cédric Coulonges, Pierre-...
WABI
2010
Springer
178views Bioinformatics» more  WABI 2010»
13 years 3 months ago
Haplotype Inference on Pedigrees with Recombinations and Mutations
Abstract. Haplotype Inference (HI) is a computational challenge of crucial importance in a range of genetic studies, such as functional genomics, pharmacogenetics and population ge...
Yuri Pirola, Paola Bonizzoni, Tao Jiang
BMCBI
2011
12 years 8 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu
SP
2008
IEEE
122views Security Privacy» more  SP 2008»
13 years 4 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...