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» Some statistical properties of regulatory DNA sequences, and...
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BMCBI
2010
152views more  BMCBI 2010»
13 years 5 months ago
FITBAR: a web tool for the robust prediction of prokaryotic regulons
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
Jacques Oberto
BMCBI
2006
108views more  BMCBI 2006»
13 years 5 months ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
BMCBI
2008
123views more  BMCBI 2008»
13 years 5 months ago
Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach
Background: Eukaryotic promoter prediction using computational analysis techniques is one of the most difficult jobs in computational genomics that is essential for constructing a...
Firoz Anwar, Syed Murtuza Baker, Taskeed Jabid, Md...
IMSCCS
2006
IEEE
13 years 11 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
BMCBI
2010
121views more  BMCBI 2010»
13 years 5 months ago
Reconstructing genome trees of prokaryotes using overlapping genes
Background: Overlapping genes (OGs) are defined as adjacent genes whose coding sequences overlap partially or entirely. In fact, they are ubiquitous in microbial genomes and more ...
Chih-Hsien Cheng, Chung-Han Yang, Hsien-Tai Chiu, ...