Sciweavers

Share
BMCBI
2008

Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach

11 years 8 months ago
Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach
Background: Eukaryotic promoter prediction using computational analysis techniques is one of the most difficult jobs in computational genomics that is essential for constructing and understanding genetic regulatory networks. The increased availability of sequence data for various eukaryotic organisms in recent years has necessitated for better tools and techniques for the prediction and analysis of promoters in eukaryotic sequences. Many promoter prediction methods and tools have been developed to date but they have yet to provide acceptable predictive performance. One obvious criteria to improve on current methods is to devise a better system for selecting appropriate features of promoters that distinguish them from non-promoters. Secondly improved performance can be achieved by enhancing the predictive ability of the machine learning algorithms used. Results: In this paper, a novel approach is presented in which 128 4-mer motifs in conjunction with a non-linear machine-learning algo...
Firoz Anwar, Syed Murtuza Baker, Taskeed Jabid, Md
Added 09 Dec 2010
Updated 09 Dec 2010
Type Journal
Year 2008
Where BMCBI
Authors Firoz Anwar, Syed Murtuza Baker, Taskeed Jabid, Md. Mehedi Hasan, Mohammad Shoyaib, Haseena Khan, Ray Walshe
Comments (0)
books