6 search results - page 1 / 2 » Specificity Normalization for Identifying Selective Inhibito... |
BIOCOMP
2008
13 years 6 months ago
2008
ct The enrichment and recall of known inhibitors in a virtual screen are correlated with the probability of finding effective inhibitors through this process. In practice, a large ...
BMCBI
2010
13 years 4 months ago
2010
Background: An explosive global spreading of multidrug resistant Mycobacterium tuberculosis (Mtb) is a catastrophe, which demands an urgent need to design or develop novel/potent ...
BMCBI
2007
13 years 4 months ago
2007
Background: Peptide ligands have tremendous therapeutic potential as efficacious drugs. Currently, more than 40 peptides are available in the market for a drug. However, since cos...
BMCBI
2008
13 years 4 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
BMCBI
2010
13 years 4 months ago
2010
Background: Several bioinformatic approaches have previously been used to find novel sites of ADAR mediated A-to-I RNA editing in human. These studies have discovered thousands of...