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BMCBI
2010
146views more  BMCBI 2010»
13 years 5 months ago
Revealing and avoiding bias in semantic similarity scores for protein pairs
Background: Semantic similarity scores for protein pairs are widely applied in functional genomic researches for finding functional clusters of proteins, predicting protein functi...
Jing Wang 0004, Xianxiao Zhou, Jing Zhu, Chenggui ...
BMCBI
2008
158views more  BMCBI 2008»
13 years 5 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
BMCBI
2008
149views more  BMCBI 2008»
13 years 5 months ago
Clustering of cognate proteins among distinct proteomes derived from multiple links to a single seed sequence
Background: Modern proteomes evolved by modification of pre-existing ones. It is extremely important to comparative biology that related proteins be identified as members of the s...
Adriano Barbosa-Silva, Venkata P. Satagopam, Reinh...
BMCBI
2005
163views more  BMCBI 2005»
13 years 5 months ago
Alkahest NuclearBLAST: a user-friendly BLAST management and analysis system
Background -: Sequencing of EST and BAC end datasets is no longer limited to large research groups. Drops in per-base pricing have made high throughput sequencing accessible to in...
Stephen E. Diener, Thomas D. Houfek, Sam E. Kalat,...
BIBM
2010
IEEE
157views Bioinformatics» more  BIBM 2010»
13 years 3 months ago
Decomposing PPI networks for complex discovery
Abstract--Protein complexes are important for understanding principles of cellular organization and functions. With the availability of large amounts of high-throughput proteinprot...
Guimei Liu, Chern Han Yong, Limsoon Wong, Hon Nian...