Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
The tryptophan operon of E. coli represents an important regulatory unit consisting of multiple feedback loops. The role of these loops is crucial to understand the dynamics of tr...
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
Andrew K. Rider, Geoffrey Siwo, Nitesh V. Chawla, ...
— With the rapid growth of Internet, parameter design and analysis for large-scale networks has become a topic of active interest. Since simulation of such large scale systems is...