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BMCBI
2011
12 years 9 months ago
Detection of recurrent rearrangement breakpoints from copy number data
Background: Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array compara...
Anna M. Ritz, Pamela L. Paris, Michael Ittmann, Co...
ITNG
2007
IEEE
13 years 11 months ago
Sorting by Block-Interchanges and Signed Reversals
A block-interchange is a rearrangement event that exchanges two, not necessarily consecutive, contiguous regions in a genome, maintaining the original orientation. Signed reversal...
Cleber V. G. Mira, Joao Meidanis
BMCBI
2008
154views more  BMCBI 2008»
13 years 5 months ago
GenomeMatcher: A graphical user interface for DNA sequence comparison
Background: The number of available genome sequences is increasing, and easy-to-use software that enables efficient comparative analysis is needed. Results: We developed GenomeMat...
Yoshiyuki Ohtsubo, Wakako Ikeda-Ohtsubo, Yuji Naga...
BMCBI
2006
192views more  BMCBI 2006»
13 years 5 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...
CIBCB
2007
IEEE
13 years 11 months ago
An Experimental Evaluation of Inversion-and Transposition-Based Genomic Distances through Simulations
— Rearrangements of genes and other syntenic blocks have become a topic of intensive study by phylogenists, comparative genomicists, and computational biologists: they are a feat...
Moulik Kothari, Bernard M. E. Moret