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» Statistical Characterization of Protein Ensembles
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TCBB
2008
108views more  TCBB 2008»
13 years 4 months ago
Statistical Characterization of Protein Ensembles
When accounting for structural fluctuations or measurement errors, a single rigid structure may not be sufficient to represent a protein. One approach to solve this problem is to r...
Diego Rother, Guillermo Sapiro, Vijay Pande
BMCBI
2006
163views more  BMCBI 2006»
13 years 4 months ago
Ensemble attribute profile clustering: discovering and characterizing groups of genes with similar patterns of biological featur
Background: Ensemble attribute profile clustering is a novel, text-based strategy for analyzing a userdefined list of genes and/or proteins. The strategy exploits annotation data ...
J. R. Semeiks, A. Rizki, Mina J. Bissell, I. Saira...
ISMB
2000
13 years 6 months ago
Prediction of the Number of Residue Contacts in Proteins
Knowing the number of residue contacts in a protein is crucial for deriving constraints useful in modeling protein folding, protein structure, and/or scoring remote homology searc...
Piero Fariselli, Rita Casadio
BMCBI
2010
153views more  BMCBI 2010»
13 years 4 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
MCS
2010
Springer
13 years 9 months ago
An Experimental Comparison of Hierarchical Bayes and True Path Rule Ensembles for Protein Function Prediction
Abstract. The computational genome-wide annotation of gene functions requires the prediction of hierarchically structured functional classes and can be formalized as a multiclass, ...
Matteo Re, Giorgio Valentini