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» Statistical test for consistent estimation of causal effects...
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BMCBI
2008
242views more  BMCBI 2008»
13 years 5 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
BMCBI
2008
186views more  BMCBI 2008»
13 years 5 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
WSC
2000
13 years 6 months ago
A comparison of five steady-state truncation heuristics for simulation
We compare the performance of five well-known truncation heuristics for mitigating the effects of initialization bias in the output analysis of steady-state simulations. Two of th...
K. Preston White, Michael J. Cobb, Stephen C. Spra...
BMCBI
2007
146views more  BMCBI 2007»
13 years 5 months ago
PubMed related articles: a probabilistic topic-based model for content similarity
Background: We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document ...
Jimmy J. Lin, W. John Wilbur
BMCBI
2010
149views more  BMCBI 2010»
13 years 5 months ago
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
Sigrid Rouam, Thierry Moreau, Philippe Broët