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BMCBI
2004
128views more  BMCBI 2004»
13 years 5 months ago
Structural characterization of genomes by large scale sequence-structure threading: application of reliability analysis in struc
Background: We establish that the occurrence of protein folds among genomes can be accurately described with a Weibull function. Systems which exhibit Weibull character can be int...
Artem Cherkasov, Shannan J. Ho Sui, Robert C. Brun...
BMCBI
2004
127views more  BMCBI 2004»
13 years 5 months ago
MolTalk - a programming library for protein structures and structure analysis
Background: Two of the mostly unsolved but increasingly urgent problems for modern biologists are a) to quickly and easily analyse protein structures and b) to comprehensively min...
Alexander V. Diemand, Holger Scheib
GECCO
2009
Springer
148views Optimization» more  GECCO 2009»
14 years 18 days ago
An evolutionary approach to constructive induction for link discovery
This paper presents a genetic programming-based symbolic regression approach to the construction of relational features in link analysis applications. Specifically, we consider t...
Tim Weninger, William H. Hsu, Jing Xia, Waleed Alj...
BMCBI
2010
153views more  BMCBI 2010»
13 years 6 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
BMCBI
2007
180views more  BMCBI 2007»
13 years 6 months ago
Splicy: a web-based tool for the prediction of possible alternative splicing events from Affymetrix probeset data
Background: The Affymetrix™ technology is nowadays a well-established method for the analysis of gene expression profiles in cancer research studies. However, changes in gene ex...
Davide Rambaldi, Barbara Felice, Viviane Praz, Phi...