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» Symbolic reachability analysis of genetic regulatory network...
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HYBRID
2007
Springer
13 years 11 months ago
Model Checking Genetic Regulatory Networks with Parameter Uncertainty
The lack of precise numerical information for the values of biological parameters severely limits the development and analysis of models of genetic regulatory networks. To deal wit...
Grégory Batt, Calin Belta, Ron Weiss
RECOMB
2005
Springer
14 years 5 months ago
Combinatorial Genetic Regulatory Network Analysis Tools for High Throughput Transcriptomic Data
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...
Elissa J. Chesler, Michael A. Langston
HYBRID
2004
Springer
13 years 10 months ago
Understanding the Bacterial Stringent Response Using Reachability Analysis of Hybrid Systems
Abstract. In this paper we model coupled genetic and metabolic networks as hybrid systems. The vector fields are multi - affine, i.e., have only product - type nonlinearities to a...
Calin Belta, Peter Finin, Luc C. G. J. M. Habets, ...
HYBRID
2001
Springer
13 years 9 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic
ICFEM
2010
Springer
13 years 3 months ago
Making the Right Cut in Model Checking Data-Intensive Timed Systems
Abstract. The success of industrial-scale model checkers such as Uppaal [3] or NuSMV [12] relies on the efficiency of their respective symbolic state space representations. While d...
Rüdiger Ehlers, Michael Gerke 0002, Hans-J&ou...