—Accumulating evidence suggests that biological systems exhibit modular organization. Accurate identification of modularity is vital for understanding this organization. A recen...
Roger L. Chang, Feng Luo, Stuart Johnson, Richard ...
Biomodel engineering is the science of designing, constructing and analyzing computational models of biological systems. It forms a systematic and powerful extension of earlier mat...
Rainer Breitling, Robin Donaldson, David R. Gilber...
Background: Cells dynamically adapt their gene expression patterns in response to various stimuli. This response is orchestrated into a number of gene expression modules consistin...
Jochen Supper, Martin Strauch, Dierk Wanke, Klaus ...
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
The HYDRA work provides insight into the exploitation of holistic behavioural and morphological adaptation in the design of new artefacts. The potential of the new design principle...