23 search results - page 4 / 5 » TOPOFIT-DB, a database of protein structural alignments base... |
BMCBI
2004
13 years 5 months ago
2004
Background: The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based com...
BMCBI
2011
12 years 9 months ago
2011
Background: Conotoxin has been proven to be effective in drug design and could be used to treat various disorders such as schizophrenia, neuromuscular disorders and chronic pain. ...
BMCBI
2008
13 years 5 months ago
2008
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
NAR
2007
13 years 4 months ago
2007
COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles f...
BMCBI
2005
13 years 5 months ago
2005
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...