Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
We present a probabilistic framework that models the process by which transcriptional binding explains the mRNA expression of different genes. Our joint probabilistic model unifie...
Eran Segal, Yoseph Barash, Itamar Simon, Nir Fried...
Background: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR protein...
We introduce three ensemble machine learning methods for analysis of biological DNA binding by transcription factors (TFs). The goal is to identify both TF target genes and their ...
Background: MicroRNAs (miRs) are small noncoding RNAs that bind to complementary/partially complementary sites in the 3' untranslated regions of target genes to regulate prot...
Jishou Ruan, Hanzhe Chen, Lukasz A. Kurgan, Ke Che...