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BMCBI
2010
118views more  BMCBI 2010»
13 years 4 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
BMCBI
2010
167views more  BMCBI 2010»
13 years 4 months ago
Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of met
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
Melissa J. Morine, Jolene McMonagle, Sinead Toomey...
BMCBI
2008
110views more  BMCBI 2008»
13 years 4 months ago
Testing for treatment effects on gene ontology
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...
Taewon Lee, Varsha G. Desai, Cruz Velasco, Robert ...
CSB
2003
IEEE
150views Bioinformatics» more  CSB 2003»
13 years 9 months ago
Algorithms for Bounded-Error Correlation of High Dimensional Data in Microarray Experiments
The problem of clustering continuous valued data has been well studied in literature. Its application to microarray analysis relies on such algorithms as -means, dimensionality re...
Mehmet Koyutürk, Ananth Grama, Wojciech Szpan...
BMCBI
2011
12 years 8 months ago
Gene set analysis for longitudinal gene expression data
Background: Gene set analysis (GSA) has become a successful tool to interpret gene expression profiles in terms of biological functions, molecular pathways, or genomic locations. ...
Ke Zhang, Haiyan Wang, Arne C. Bathke, Solomon W. ...