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TCS
2011
13 years 7 days ago
The transposition median problem is NP-complete
During the last years, the genomes of more and more species have been sequenced, providing data for phylogenetic reconstruction based on genome rearrangement measures, where the m...
Martin Bader
JDA
2007
156views more  JDA 2007»
13 years 5 months ago
A linear time algorithm for the inversion median problem in circular bacterial genomes
In the median problem, we are given a distance or dissimilarity measure d, three genomes G1, G2, and G3, and we want to find a genome G (a median) such that the sum 3 i=1 d(G, Gi...
Enno Ohlebusch, Mohamed Ibrahim Abouelhoda, Kathri...
WABI
2001
Springer
112views Bioinformatics» more  WABI 2001»
13 years 9 months ago
Finding an Optimal Inversion Median: Experimental Results
We derive a branch-and-bound algorithm to find an optimal inversion median of three signed permutations. The algorithm prunes to manageable size an extremely large search tree usi...
Adam C. Siepel, Bernard M. E. Moret
EVOW
2004
Springer
13 years 10 months ago
Evolutionary Design Space Exploration for Median Circuits
This paper shows that it is possible to (1) discover novel implementations of median circuits using evolutionary techniques and (2) find out suitable median circuits in case that ...
Lukás Sekanina
BMCBI
2010
95views more  BMCBI 2010»
13 years 5 months ago
Heuristics for the inversion median problem
Background: The study of genome rearrangements has become a mainstay of phylogenetics and comparative genomics. Fundamental in such a study is the median problem: given three geno...
Vaibhav Rajan, Andrew Wei Xu, Yu Lin, Krister M. S...