153 search results - page 2 / 31 » The Pfam protein families database |
BMCBI
2006
13 years 4 months ago
2006
Background: Proteins are comprised of one or several building blocks, known as domains. Such domains can be classified into families according to their evolutionary origin. Wherea...
ECCB
2008
IEEE
13 years 11 months ago
2008
IEEE
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
BMCBI
2007
13 years 5 months ago
2007
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
BMCBI
2004
13 years 4 months ago
2004
Background: It is well known that different species have different protein domain repertoires, and indeed that some protein domains are kingdom specific. This information has not ...
BMCBI
2010
12 years 12 months ago
2010
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...