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CPM
2004
Springer
168views Combinatorics» more  CPM 2004»
13 years 10 months ago
The Protein Sequence Design Problem in Canonical Model on 2D and 3D Lattices
In this paper we investigate the protein sequence design (PSD) problem (also known as the inverse protein folding problem) under the Canonical model 4 on 2D and 3D lattices [12, 25...
Piotr Berman, Bhaskar DasGupta, Dhruv Mubayi, Robe...
BMCBI
2005
152views more  BMCBI 2005»
13 years 4 months ago
An ant colony optimisation algorithm for the 2D and 3D hydrophobic polar protein folding problem
Background: The protein folding problem is a fundamental problems in computational molecular biology and biochemical physics. Various optimisation methods have been applied to for...
Alena Shmygelska, Holger H. Hoos
BMCBI
2008
211views more  BMCBI 2008»
13 years 4 months ago
CPSP-tools - Exact and complete algorithms for high-throughput 3D lattice protein studies
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...
Martin Mann, Sebastian Will, Rolf Backofen
BMCBI
2007
216views more  BMCBI 2007»
13 years 4 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
BIRD
2008
Springer
109views Bioinformatics» more  BIRD 2008»
13 years 6 months ago
A Robust Class of Stable Proteins in the 2D HPC Model
The inverse protein folding problem is that of designing an amino acid sequence which has a prescribed native protein fold. This problem arises in drug design where a particular st...
Alireza Hadj Khodabakhshi, Ján Manuch, Aras...