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BMCBI
2008
167views more  BMCBI 2008»
13 years 5 months ago
Not proper ROC curves as new tool for the analysis of differentially expressed genes in microarray experiments
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Stefano Parodi, Vito Pistoia, Marco Muselli
BMCBI
2010
181views more  BMCBI 2010»
13 years 5 months ago
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
Amit Zeisel, Amnon Amir, Wolfgang J. Köstler,...
JCB
2000
103views more  JCB 2000»
13 years 5 months ago
Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data
Although two-color uorescent DNA microarrays are now standard equipment in many molecular biology laboratories, methods for identifying differentially expressed genes in microarra...
Trey Ideker, Vesteinn Thorsson, Andrew F. Siegel, ...
CIBCB
2006
IEEE
13 years 11 months ago
A Model-Free Greedy Gene Selection for Microarray Sample Class Prediction
— Microarray data analysis is notoriously challenging as it involves a huge number of genes compared to only a limited number of samples. Gene selection, to detect the most signi...
Yi Shi, Zhipeng Cai, Lizhe Xu, Wei Ren, Randy Goeb...
BMCBI
2006
129views more  BMCBI 2006»
13 years 5 months ago
Identifying genes that contribute most to good classification in microarrays
Background: The goal of most microarray studies is either the identification of genes that are most differentially expressed or the creation of a good classification rule. The dis...
Stuart G. Baker, Barnett S. Kramer