12 search results - page 2 / 3 » The inverse protein folding problem on 2D and 3D lattices |
BMCBI
2007
13 years 5 months ago
2007
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
BIRD
2008
Springer
13 years 7 months ago
2008
Springer
The inverse protein folding problem is that of designing an amino acid sequence which has a prescribed native protein fold. This problem arises in drug design where a particular st...
BMCBI
2008
13 years 5 months ago
2008
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...
LATIN
2004
Springer
13 years 10 months ago
2004
Springer
We consider the problem of protein folding in the HP model on the 3D square lattice. This problem is combinatorially equivalent to folding a string of 0’s and 1’s so that the s...
BMCBI
2010
13 years 5 months ago
2010
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...