We present an extension of the standard partition function approach to RNA secondary structures that computes the probabilities Pu[i, j] that a sequence interval [i, j] is unpaired...
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from...
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...
Background: While microarrays are the predominant method for gene expression profiling, probe signal variation is still an area of active research. Probe signal is sequence depend...