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DNA
2006
Springer
130views Bioinformatics» more  DNA 2006»
13 years 7 months ago
Displacement Whiplash PCR: Optimized Architecture and Experimental Validation
Whiplash PCR-based methods of biomolecular computation (BMC), while highly-versatile in principle, are well-known to suffer from a simple but serious form of self-poisoning known a...
John A. Rose, Ken Komiya, Satsuki Yaegashi, Masami...
DNA
2008
Springer
13 years 6 months ago
A Simple DNA Gate Motif for Synthesizing Large-Scale Circuits
The prospects of programming molecular systems to perform complex autonomous tasks has motivated research into the design of synthetic biochemical circuits. Of particular interest ...
Lulu Qian, Erik Winfree
NC
2006
13 years 4 months ago
A DNA Superstructure-based Replicator without Product Inhibition
A monomer structure based on a hairpin loop is described that can be linked via short oligonucleotide sequences (linkers) to form polymers. Independence of linked monomers allow fo...
David Y. Zhang, Bernard Yurke
DNA
2008
Springer
121views Bioinformatics» more  DNA 2008»
13 years 6 months ago
Isothermal Reactivating Whiplash PCR for Locally Programmable Molecular Computation
Whiplash PCR (WPCR), due to Hagiya et al. [1], is a novel technique for autonomous molecular computation where a state machine is implemented with a single stranded DNA molecule a...
John H. Reif, Urmi Majumder
DNA
2007
Springer
159views Bioinformatics» more  DNA 2007»
13 years 11 months ago
Activatable Tiles: Compact, Robust Programmable Assembly and Other Applications
While algorithmic DNA self-assembly is, in theory, capable of forming complex patterns, its experimental demonstration has been limited by significant assembly errors. In this pa...
Urmi Majumder, Thomas H. LaBean, John H. Reif