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BMCBI
2010
125views more  BMCBI 2010»
13 years 5 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
BMCBI
2010
176views more  BMCBI 2010»
13 years 5 months ago
TargetSpy: a supervised machine learning approach for microRNA target prediction
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
13 years 11 months ago
Peptide Charge State Determination for Low-Resolution Tandem Mass Spectra
Mass spectrometry is a particularly useful technology for the rapid and robust identification of peptides and proteins in complex mixtures. Peptide sequences can be identified b...
Aaron A. Klammer, Christine C. Wu, Michael J. MacC...
ICML
2009
IEEE
14 years 6 months ago
Robust bounds for classification via selective sampling
We introduce a new algorithm for binary classification in the selective sampling protocol. Our algorithm uses Regularized Least Squares (RLS) as base classifier, and for this reas...
Nicolò Cesa-Bianchi, Claudio Gentile, Franc...
BMCBI
2010
118views more  BMCBI 2010»
13 years 5 months ago
From learning taxonomies to phylogenetic learning: Integration of 16S rRNA gene data into FAME-based bacterial classification
Background: Machine learning techniques have shown to improve bacterial species classification based on fatty acid methyl ester (FAME) data. Nonetheless, FAME analysis has a limit...
Bram Slabbinck, Willem Waegeman, Peter Dawyndt, Pa...