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» Using ESTs to improve the accuracy of de novo gene predictio...
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BMCBI
2007
147views more  BMCBI 2007»
13 years 5 months ago
Improved residue contact prediction using support vector machines and a large feature set
Background: Predicting protein residue-residue contacts is an important 2D prediction task. It is useful for ab initio structure prediction and understanding protein folding. In s...
Jianlin Cheng, Pierre Baldi
BMCBI
2006
136views more  BMCBI 2006»
13 years 4 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara
BMCBI
2010
113views more  BMCBI 2010»
13 years 5 months ago
A classification model for distinguishing copy number variants from cancer-related alterations
Background: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in compa...
Irina Ostrovnaya, Gouri Nanjangud, Adam B. Olshen
ISMB
2004
13 years 6 months ago
Predicting gene regulation by sigma factors in Bacillus subtilis from genome-wide data
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
BMCBI
2007
105views more  BMCBI 2007»
13 years 5 months ago
HoxPred: automated classification of Hox proteins using combinations of generalised profiles
Background: Correct identification of individual Hox proteins is an essential basis for their study in diverse research fields. Common methods to classify Hox proteins focus on th...
Morgane Thomas-Chollier, Luc Leyns, Valérie...