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IPPS
2003
IEEE
13 years 10 months ago
Using Hybrid Alignment for Iterative Sequence Database Searches
Progressive sequence model refinement by means of iterative searches is an effective technique for high sensitivity database searches and is currently employed in popular tools s...
Yuheng Li, Mario Lauria, Ralf Bundschuh
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
CP
2003
Springer
13 years 10 months ago
A SAT-Based Approach to Multiple Sequence Alignment
Multiple sequence alignment is a central problem in Bioinformatics. A known integer programming approach is to apply branch-and-cut to exponentially large graph-theoretic models. T...
Steven David Prestwich, Desmond G. Higgins, Orla O...
GCB
2001
Springer
67views Biometrics» more  GCB 2001»
13 years 9 months ago
Sequence Database Search Using Jumping Alignments
Constantin Bannert, Marc Rehmsmeier, Rainer Spang,...
DATESO
2007
157views Database» more  DATESO 2007»
13 years 6 months ago
Index-Based Approach to Similarity Search in Protein and Nucleotide Databases
When searching databases of nucleotide or protein sequences, finding a local alignment of two sequences is one of the main tasks. Since the sizes of available databases grow const...
David Hoksza, Tomás Skopal