820 search results - page 1 / 164 » Using Multiple Alignments to Improve Gene Prediction |
RECOMB
2005
Springer
14 years 5 months ago
2005
Springer
The multiple species de novo gene prediction problem can be stated as follows: given an alignment of genomic sequences from two or more organisms, predict the location and structur...
BMCBI
2011
12 years 9 months ago
2011
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
BMCBI
2006
13 years 5 months ago
2006
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
BMCBI
2006
13 years 5 months ago
2006
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
RECOMB
2004
Springer
14 years 5 months ago
2004
Springer
The Gibbs sampling method has been widely used for sequence analysis after it was successfully applied to the problem of identifying regulatory motif sequences upstream of genes. ...