128 search results - page 4 / 26 » Using large-scale perturbations in gene network reconstructi... |
BIOINFORMATICS
2011
13 years 1 months ago
2011
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
BMCBI
2010
13 years 6 months ago
2010
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
BMCBI
2006
13 years 6 months ago
2006
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
NAR
2002
13 years 5 months ago
2002
The prediction of operons, the smallest unit of transcription in prokaryotes, is the first step towards reconstruction of a regulatory network at the whole genome level. Sequence ...
BMCBI
2011
12 years 9 months ago
2011
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...