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» VIGOR, an annotation program for small viral genomes
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BMCBI
2008
95views more  BMCBI 2008»
13 years 5 months ago
Universal seeds for cDNA-to-genome comparison
Background: To meet the needs of gene annotation for newly sequenced organisms, optimized spaced seeds can be implemented into cross-species sequence alignment programs to accurat...
Leming Zhou, Jonathan Stanton, Liliana Florea
WABI
2007
Springer
102views Bioinformatics» more  WABI 2007»
13 years 11 months ago
Homology Search with Fragmented Nucleic Acid Sequence Patterns
The comprehensive annotation of non-coding RNAs in newly sequenced genomes is still a largely unsolved problem because many functional RNAs exhibit not only poorly conserved sequen...
Axel Mosig, Julian J.-L. Chen, Peter F. Stadler
BMCBI
2010
98views more  BMCBI 2010»
13 years 5 months ago
miRMaid: a unified programming interface for microRNA data resources
Background: MicroRNAs (miRNAs) are endogenous small RNAs that play a key role in post-transcriptional regulation of gene expression in animals and plants. The number of known miRN...
Anders Jacobsen, Anders Krogh, Sakari Kauppinen, M...
BMCBI
2005
142views more  BMCBI 2005»
13 years 5 months ago
CLU: A new algorithm for EST clustering
Background: The continuous flow of EST data remains one of the richest sources for discoveries in modern biology. The first step in EST data mining is usually associated with EST ...
Andrey A. Ptitsyn, Winston Hide
BMCBI
2007
147views more  BMCBI 2007»
13 years 5 months ago
Hon-yaku: a biology-driven Bayesian methodology for identifying translation initiation sites in prokaryotes
Background: Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remain...
Yuko Makita, Michiel J. L. de Hoon, Antoine Danchi...