32 search results - page 1 / 7 » Visualization-based discovery and analysis of genomic aberra... |
BMCBI
2005
13 years 4 months ago
2005
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
BMCBI
2011
12 years 8 months ago
2011
Background: Copy number aberrations (CNAs) are an important molecular signature in cancer initiation, development, and progression. However, these aberrations span a wide range of...
BMCBI
2010
13 years 5 months ago
2010
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
BMCBI
2007
13 years 4 months ago
2007
Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
RECOMB
2006
Springer
14 years 5 months ago
2006
Springer
Permutation of class labels is a common approach to build null distributions for significance analyis of microarray data. It is assumed to produce random score distributions, which...