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ALMOB
2007
170views more  ALMOB 2007»
13 years 5 months ago
A spatio-temporal mining approach towards summarizing and analyzing protein folding trajectories
Understanding the protein folding mechanism remains a grand challenge in structural biology. In the past several years, computational theories in molecular dynamics have been empl...
Hui Yang, Srinivasan Parthasarathy, Duygu Ucar
ALMOB
2007
133views more  ALMOB 2007»
13 years 5 months ago
Characteristics of predictor sets found using differential prioritization
Background: Feature selection plays an undeniably important role in classification problems involving high dimensional datasets such as microarray datasets. For filter-based featu...
Chia Huey Ooi, Madhu Chetty, Shyh Wei Teng
ALMOB
2007
74views more  ALMOB 2007»
13 years 5 months ago
Evaluating deterministic motif significance measures in protein databases
Background: Assessing the outcome of motif mining algorithms is an essential task, as the number of reported motifs can be very large. Significance measures play a central role in...
Pedro Gabriel Ferreira, Paulo J. Azevedo
ALMOB
2007
151views more  ALMOB 2007»
13 years 5 months ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
ALMOB
2007
111views more  ALMOB 2007»
13 years 5 months ago
Transcriptional regulatory network discovery via multiple method integration: application to e. coli K12
Motivation: Transcriptional regulatory network (TRN) discovery from one method (e.g. microarray analysis, gene ontology, phylogenic similarity) does not seem feasible due to lack ...
Jingjun Sun, Kagan Tuncay, Alaa Abi Haidar, Lisa E...