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BIOCOMP
2008
13 years 6 months ago
Discoveries in shRNA Design
-- To successfully apply RNAi, the very first step is to design functional siRNA or shRNA sequences targeting specific genes. Many characteristics of functional synthetic siRNAs ha...
Hong Zhou, Xiao Zeng, Joseph Manthey
BIOCOMP
2008
13 years 6 months ago
Prediction of Protein Function Using Graph Container and Message Passing
We introduce a novel parameter called container flux, which is used to measure the information sharing capacity between two distinct nodes in a graph. Other useful information, bot...
Hongbo Zhou, Qiang Shawn Cheng, Mehdi Zargham
BIOCOMP
2008
13 years 6 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...