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BMCBI
2011
12 years 9 months ago
AMDORAP: Non-targeted metabolic profiling based on high-resolution LC-MS
Background: Liquid chromatography-mass spectrometry (LC-MS) utilizing the high-resolution power of an orbitrap is an important analytical technique for both metabolomics and prote...
Hiroki Takahashi, Takuya Morimoto, Naotake Ogasawa...
BMCBI
2011
12 years 9 months ago
New Words in Human Mutagenesis
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
Alexander Y. Panchin, Sergey I. Mitrofanov, Andrei...
BMCBI
2011
13 years 1 months ago
Learning genetic epistasis using Bayesian network scoring criteria
Background: Gene-gene epistatic interactions likely play an important role in the genetic basis of many common diseases. Recently, machine-learning and data mining methods have be...
Xia Jiang, Richard E. Neapolitan, M. Michael Barma...
BMCBI
2011
13 years 1 months ago
ASPDock: protein-protein docking algorithm using atomic solvation parameters model
Background: Atomic Solvation Parameters (ASP) model has been proven to be a very successful method of calculating the binding free energy of protein complexes. This suggests that ...
Lin Li, Dachuan Guo, Yangyu Huang, Shiyong Liu, Yi...
BMCBI
2011
13 years 1 months ago
PileLine: a toolbox to handle genome position information in next-generation sequencing studies
Background: Genomic position (GP) files currently used in next-generation sequencing (NGS) studies are always difficult to manipulate due to their huge size and the lack of approp...
Daniel Glez-Peña, Gonzalo Gómez-L&oa...