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CANDC
2006
ACM
13 years 4 months ago
Unraveling the nature of the segmentation clock: Intrinsic disorder of clock proteins and their interaction map
Vertebrate segmentation has been proved to be under a strict temporal control governed by a biological clock, known as the segmentation clock. The present experimental evidence su...
Sourav Roy, Santiago Schnell, Predrag Radivojac
CANDC
2007
ACM
13 years 4 months ago
Codon phylogenetic distance
We develop here an analytical evolution model based on a trinucleotide mutation matrix 64 × 64 with nine substitution parameters associated with the three types of substitutions ...
Christian J. Michel
CANDC
2006
ACM
13 years 4 months ago
Prediction of protein subcellular location using hydrophobic patterns of amino acid sequence
The function of eukaryotic protein is closely correlated with its subcellular location. The number of newly found protein sequences entering into data banks is rapidly increasing ...
Tongliang Zhang, Yongsheng Ding, Kuo-Chen Chou
CANDC
2006
ACM
13 years 4 months ago
Why substrate depletion has apparent first-order kinetics in enzymatic digestion
A number of enzyme digestion assays show apparent first-order kinetics of reactant depletion. There are four possible explanations of this phenomenon: (i) the reaction is dominate...
Jeyaraman Srividhya, Santiago Schnell
CANDC
2006
ACM
13 years 4 months ago
Hydrophobic collapse in (in silico) protein folding
A model of hydrophobic collapse, which is treated as the driving force for protein folding, is presented. This model is the superposition of three models commonly used in protein ...
Michal Brylinski, Leszek Konieczny, Irena Roterman