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BIOINFORMATICS
2005
169views more  BIOINFORMATICS 2005»
13 years 5 months ago
A statistical model providing comprehensive predictions for the mRNA differential display
s Dirk Tremmel, Maximilian Tropschug N. crassa FKBP22 is part of a protein folding helper complex in the ER [oral presentation] Manuela Heiner A carbamate-cleaving catalytic antibo...
David Meintrup, Ellen Reisinger
BMCBI
2007
94views more  BMCBI 2007»
13 years 5 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
BMCBI
2007
183views more  BMCBI 2007»
13 years 5 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
BMCBI
2010
89views more  BMCBI 2010»
13 years 5 months ago
Predictors of natively unfolded proteins: unanimous consensus score to detect a twilight zone between order and disorder in gene
Background: Natively unfolded proteins lack a well defined three dimensional structure but have important biological functions, suggesting a re-assignment of the structure-functio...
Antonio Deiana, Andrea Giansanti
BMCBI
2007
165views more  BMCBI 2007»
13 years 5 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf