Abstract. DNA copy number is the number of replicates of a contiguous segment of DNA on the genome. Copy number alteration (CNA) is a genetic abnormality in which the number of the...
Identifying gene regulatory networks from high-throughput gene expression data is one of the most important goals of bioinformatics, but it remains difficult to define what makes a...
Abstract. We investigate the problem of inferring contiguous ancestral regions (CARs) of the genome of the last common ancestor of all extant amniotes, based on the currently seque...
Cheng and Church proposed a greedy deletion-addition algorithm to find a given number of k biclusters, whose mean squared residues (MSRs) are below certain thresholds and the miss...
Stefan Gremalschi, Gulsah Altun, Irina Astrovskaya...
Abstract. Accurate inference of local ancestry from whole-genome genetic variation data is critical for understanding the history of admixed human populations and detecting SNPs as...