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ISBRA
2009
Springer
13 years 11 months ago
A Linear-Time Algorithm for Analyzing Array CGH Data Using Log Ratio Triangulation
Abstract. DNA copy number is the number of replicates of a contiguous segment of DNA on the genome. Copy number alteration (CNA) is a genetic abnormality in which the number of the...
Matthew Hayes, Jing Li
ISBRA
2009
Springer
13 years 11 months ago
Using Gene Expression Modeling to Determine Biological Relevance of Putative Regulatory Networks
Identifying gene regulatory networks from high-throughput gene expression data is one of the most important goals of bioinformatics, but it remains difficult to define what makes a...
Peter Larsen, Yang Dai
ISBRA
2009
Springer
13 years 11 months ago
Prediction of Contiguous Regions in the Amniote Ancestral Genome
Abstract. We investigate the problem of inferring contiguous ancestral regions (CARs) of the genome of the last common ancestor of all extant amniotes, based on the currently seque...
Aïda Ouangraoua, Frédéric Boyer...
ISBRA
2009
Springer
13 years 11 months ago
Mean Square Residue Biclustering with Missing Data and Row Inversions
Cheng and Church proposed a greedy deletion-addition algorithm to find a given number of k biclusters, whose mean squared residues (MSRs) are below certain thresholds and the miss...
Stefan Gremalschi, Gulsah Altun, Irina Astrovskaya...
ISBRA
2009
Springer
13 years 11 months ago
Imputation-Based Local Ancestry Inference in Admixed Populations
Abstract. Accurate inference of local ancestry from whole-genome genetic variation data is critical for understanding the history of admixed human populations and detecting SNPs as...
Bogdan Pasaniuc, Justin Kennedy, Ion I. Mandoiu