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ISMB
1993
13 years 6 months ago
Protein Sequencing Experiment Planning Using Analogy
Experiment design and execution is a central activity in the natural sciences. The SeqERsystem provides a general architecture for the integration of automated planning techniques...
Brian P. Kettler, Lindley Darden
ISMB
1993
13 years 6 months ago
Knowledge Discovery in GENBANK
Wedescribe various methods designed to discover knowledge in the GenBanknucleic acid sequence database. Using a grammatical model of gene structure, we create a parse tree of a ge...
Jeffery S. Aaronson, Juergen Haas, G. Christian Ov...
ISMB
1993
13 years 6 months ago
Knowledge-Based Generation of Machine-Learning Experiments: Learning with DNA Crystallography Data
Thoughit has been possible in the past to learn to predict DNAhydration patterns from crystallographic data, there is ambiguity in the choice of training data (both in terms of th...
Dawn M. Cohen, Casimir A. Kulikowski, Helen Berman
ISMB
1993
13 years 6 months ago
Probabilistic Structure Calculations: A Three-Dimensional tRNA Structure from Sequence Correlation Data
Algorithmsbasedonprobability theorycanaddressissues of uncertainty directly throughtheir representational frameworkandtheir theoryfor data combination.In this paper, wediscuss the...
Russ B. Altman
ISMB
1993
13 years 6 months ago
MultiMap: An Expert System for Automated Genetic Linkage Mapping
Withthe advent of the HumanGenomeProject. the ability to rapidly construct comprehensiveand accuratelinkage mapsbasedongenetic markerdata fromfamily studies is an absolute necessi...
Tara Cox Matise, Mark Perlin, Aravinda Chakravarti