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ISMB
2000
13 years 6 months ago
Computation and Visualization of Degenerate Repeats in Complete Genomes
The repetitive structure of genomic DNA holds many secrets to be discovered. A systematic study of repetitive DNA on a genomic or inter-genomic scale requires extensive algorithmi...
Stefan Kurtz, Enno Ohlebusch, Chris Schleiermacher...
ISMB
2000
13 years 6 months ago
Accelerating Protein Classification Using Suffix Trees
Position-specific scoring matrices have been used extensively to recognize highly conserved protein regions. We present a method for accelerating these searches using a suffix tre...
Bogdan Dorohonceanu, Craig G. Nevill-Manning
ISMB
2000
13 years 6 months ago
A Probabilistic Learning Approach to Whole-Genome Operon Prediction
We present a computational approach to predicting operons in the genomes of prokaryotic organisms. Our approach uses machine learning methods to induce predictive models for this ...
Mark Craven, David Page, Jude W. Shavlik, Joseph B...
ISMB
2000
13 years 6 months ago
Combinatorial Approaches to Finding Subtle Signals in DNA Sequences
Signal nding pattern discovery in unaligned DNA sequences is a fundamental problem in both computer science and molecular biology with important applications in locating regulator...
Pavel A. Pevzner, Sing-Hoi Sze
ISMB
2000
13 years 6 months ago
A Statistical Method for Finding Transcription Factor Binding Sites
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
Saurabh Sinha, Martin Tompa