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JCB
2008
13 years 5 months ago
2008
In this article, we propose a new method for computing rare maximal exact matches between multiple sequences. A rare match between k sequences S1; : : :; Sk is a string that occur...
JCB
2008
13 years 5 months ago
2008
Given a metabolic network in terms of its metabolites and reactions, our goal is to efficiently compute the minimal knock out sets of reactions required to block a given behaviour....
JCB
2008
13 years 5 months ago
2008
Traditionally nonrecombinant genome, i.e., mtDNA or Y chromosome, has been used for phylogeography, notably for ease of analysis. The topology of the phylogeny structure in this c...
JCB
2008
13 years 5 months ago
2008
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorit...
JCB
2008
13 years 5 months ago
2008
We define new measures of sequence similarity for oligonucleotide probe design. These new measures incorporate the nearest neighbor k-stem motifs in their definition, but can be e...