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BMCBI
2004
196views more  BMCBI 2004»
13 years 5 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
BMCBI
2002
133views more  BMCBI 2002»
13 years 5 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
ICPP
2007
IEEE
14 years 8 days ago
Efficient Parallel Algorithm for Optimal Three-Sequences Alignment
Sequence alignment is a fundamental problem in the computational biology. Many alignment methods have been proposed in the literature, such as pair-wise sequence alignment (2SA), ...
Chun-Yuan Lin, Chen Tai Huang, Yeh-Ching Chung, Ch...
NAR
2007
152views more  NAR 2007»
13 years 5 months ago
COMPASS server for remote homology inference
COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles f...
Ruslan Sadreyev, Ming Tang, Bong-Hyun Kim, Nick V....
BMCBI
2006
107views more  BMCBI 2006»
13 years 6 months ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...