In single-particle reconstruction, a 3D structure is reconstructed from a large number of randomly oriented 2D projections, using techniques related to computed tomography. Unlike ...
We study properties of multidomain proteins from a graph theoretical perspective. In particular, we demonstrate connections between properties of the domain overlap graph and certa...
Teresa M. Przytycka, George Davis, Nan Song, Danni...
Abstract. The interpretation of large-scale protein network data depends on our ability to identify significant sub-structures in the data, a computationally intensive task. Here w...
Jacob Scott, Trey Ideker, Richard M. Karp, Roded S...
Abstract. The Pathalyzer is a program for analyzing large-scale signal transduction networks. Reactions and their substrates and products are represented as transitions and places ...
David L. Dill, Merrill Knapp, Pamela Gage, Carolyn...
An accurate scoring function for database search is crucial for peptide identification using tandem mass spectrometry. Although many mathematical models have been proposed to scor...