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RECOMB
2005
Springer
14 years 6 months ago
Avoiding Local Optima in Single Particle Reconstruction
In single-particle reconstruction, a 3D structure is reconstructed from a large number of randomly oriented 2D projections, using techniques related to computed tomography. Unlike ...
Marshall W. Bern, Jindong Chen, Hao Chi Wong
RECOMB
2005
Springer
14 years 6 months ago
Graph Theoretical Insights into Evolution of Multidomain Proteins
We study properties of multidomain proteins from a graph theoretical perspective. In particular, we demonstrate connections between properties of the domain overlap graph and certa...
Teresa M. Przytycka, George Davis, Nan Song, Danni...
RECOMB
2005
Springer
14 years 6 months ago
Efficient Algorithms for Detecting Signaling Pathways in Protein Interaction Networks
Abstract. The interpretation of large-scale protein network data depends on our ability to identify significant sub-structures in the data, a computationally intensive task. Here w...
Jacob Scott, Trey Ideker, Richard M. Karp, Roded S...
RECOMB
2005
Springer
14 years 6 months ago
The Pathalyzer: A Tool for Analysis of Signal Transduction Pathways
Abstract. The Pathalyzer is a program for analyzing large-scale signal transduction networks. Reactions and their substrates and products are represented as transitions and places ...
David L. Dill, Merrill Knapp, Pamela Gage, Carolyn...
RECOMB
2005
Springer
14 years 6 months ago
A Hidden Markov Model Based Scoring Function for Mass Spectrometry Database Search
An accurate scoring function for database search is crucial for peptide identification using tandem mass spectrometry. Although many mathematical models have been proposed to scor...
Yunhu Wan, Ting Chen