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RECOMB
2008
Springer
14 years 6 months ago
Computation of Median Gene Clusters
Whole genome comparison based on gene order has become a popular approach in comparative genomics. An important task in this field is the detection of gene clusters, i.e. sets of g...
Sebastian Böcker, Katharina Jahn, Julia Mixta...
RECOMB
2008
Springer
14 years 6 months ago
Reconstructing the Evolutionary History of Complex Human Gene Clusters
Abstract. Clusters of genes that evolved from single progenitors via repeated segmental duplications present significant challenges to the generation of a truly complete human geno...
Adam C. Siepel, Eric D. Green, Giltae Song, Tom&aa...
RECOMB
2008
Springer
14 years 6 months ago
Fast and Accurate Alignment of Multiple Protein Networks
Comparative analysis of protein networks has proven to be a powerful approach for elucidating network structure and predicting protein function and interaction. A fundamental chall...
Maxim Kalaev, Vineet Bafna, Roded Sharan
RECOMB
2008
Springer
14 years 6 months ago
De Novo Sequencing of Nonribosomal Peptides
Abstract. While nonribosomal peptides (NRPs) are of tremendous pharmacological importance, there is currently no technology capable of highthroughput sequencing of NRPs. Difficulti...
Nuno Bandeira, Julio Ng, Dario Meluzzi, Roger G. L...
RECOMB
2008
Springer
14 years 6 months ago
DLIGHT - Lateral Gene Transfer Detection Using Pairwise Evolutionary Distances in a Statistical Framework
Abstract. This paper presents an algorithm to detect lateral gene transfer (LGT) on the basis of pairwise evolutionary distances. The prediction is made from a likelihood ratio der...
Christophe Dessimoz, Daniel Margadant, Gaston H. G...