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WABI
2009
Springer
128views Bioinformatics» more  WABI 2009»
13 years 11 months ago
A General Framework for Local Pairwise Alignment Statistics with Gaps
We present a novel dynamic programming framework that allows one to compute tight upper bounds for the p-values of gapped local alignments in pseudo–polynomial time. Our algorith...
Pasi Rastas
WABI
2009
Springer
156views Bioinformatics» more  WABI 2009»
13 years 11 months ago
Phylogenetic Comparative Assembly
Recent high throughput sequencing technologies are capable of generating a huge amount of data for bacterial genome sequencing projects. Although current sequence assemblers succes...
Peter Husemann, Jens Stoye
WABI
2009
Springer
128views Bioinformatics» more  WABI 2009»
13 years 11 months ago
Improving Inference of Transcriptional Regulatory Networks Based on Network Evolutionary Models
Abstract. Computational inference of transcriptional regulatory networks remains a challenging problem, in part due to the lack of strong network models. In this paper we present e...
Xiuwei Zhang, Bernard M. E. Moret
WABI
2009
Springer
162views Bioinformatics» more  WABI 2009»
13 years 11 months ago
Aligning Biomolecular Networks Using Modular Graph Kernels
Comparative analysis of biomolecular networks constructed using measurements from different conditions, tissues, and organisms offer a powerful approach to understanding the stru...
Fadi Towfic, M. Heather West Greenlee, Vasant Hona...
WABI
2009
Springer
109views Bioinformatics» more  WABI 2009»
13 years 11 months ago
Fast Prediction of RNA-RNA Interaction
Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. ...
Raheleh Salari, Rolf Backofen, Süleyman Cenk ...