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BIBE
2006
IEEE
138views Bioinformatics» more  BIBE 2006»
8 years 11 months ago
Assigning Schema Labels Using Ontology And Hueristics
Bioinformatics data is growing at a phenomenal rate. Besides the exponential growth of individual databases, the number of data depositories is increasing too. Because of the comp...
Xuan Zhang, Ruoming Jin, Gagan Agrawal
BIBE
2006
IEEE
154views Bioinformatics» more  BIBE 2006»
8 years 11 months ago
Determining Molecular Similarity for Drug Discovery using the Wavelet Riemannian Metric
Discerning the similarity between two molecules is a challenging problem in drug discovery as well as in molecular biology. The importance of this problem is due to the fact that ...
Elinor Velasquez, Emmanuel R. Yera, Rahul Singh
BIBE
2006
IEEE
160views Bioinformatics» more  BIBE 2006»
8 years 11 months ago
Methods for Random Modularization of Biological Networks
— Biological networks are formalized summaries of our knowledge about interactions among biological system components, like genes, proteins, or metabolites. From their global top...
Zachary M. Saul, Vladimir Filkov
BIBE
2006
IEEE
112views Bioinformatics» more  BIBE 2006»
8 years 11 months ago
Improving progressive alignment for phylogeny reconstruction using parsimonious guide-trees
Usman Roshan, Dennis R. Livesay, Satish Chikkagoud...
BIBE
2006
IEEE
137views Bioinformatics» more  BIBE 2006»
8 years 11 months ago
Leveraging Chemical Background Knowledge for the Prediction of Growth Inhibition
We show how chemical background knowledge can be used to improve the prediction performance in structureactivitity relationships (SARs) for non-congeneric compounds. The goal of t...
Lothar Richter, Stefan Hechtl, Stefan Kramer
BIBE
2006
IEEE
123views Bioinformatics» more  BIBE 2006»
8 years 11 months ago
Isolation and Visualization of Codon Usage Biases
While genomic sequencing projects have proved an abundant source of information for biological studies ranging from the molecular to the ecological in scale, much of the informati...
Douglas W. Raiford, Dan E. Krane, Travis E. Doom, ...
BIBE
2006
IEEE
132views Bioinformatics» more  BIBE 2006»
8 years 11 months ago
Simplicity in RNA Secondary Structure Alignment: Towards biologically plausible alignments
Ribonucleic acid (RNA) molecules contain the genetic information that regulates the functions of organisms. Given two different molecules, a preserved function corresponds to a pr...
Rimon Mikhaiel, Guohui Lin, Eleni Stroulia
BIBE
2006
IEEE
112views Bioinformatics» more  BIBE 2006»
8 years 11 months ago
Finding Correlations in Functionally Equivalent Proteins by Integrating Automated and Visual Data Exploration
The analysis of alignments of functionally equivalent proteins can reveal regularities such as correlated positions or residue patterns which are important to ensure a specific f...
Daniel A. Keim, Daniela Oelke, Royal Truman, Klaus...
BIBE
2006
IEEE
119views Bioinformatics» more  BIBE 2006»
8 years 11 months ago
Large Grain Size Stochastic Optimization Alignment
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
Perry Ridge, Hyrum Carroll, Dan Sneddon, Mark J. C...
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